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Ranking — Houston

The Best Botox & Injectables in Uptown / Galleria, Houston (2026)

5 Uptown / Galleria venues offer Botox & Injectables and clear our 4.5★, 50-plus-review quality bar. These are the best in the neighborhood, ranked by real customer reviews, local search, and AI-citation data.

Written by the WWG editorial team · Max Palmer · Updated 2026-07-18

Ranked from real customer reviews, local search performance, and AI-citation data — not paid placement.

#1Our Top Pick
1

Bare Necessities Spa + MedSpa – Upper Kirby — Esthetician-owned spa with a medspa attached

·Uptown / Galleria·$$$·LaseMD Ultra laser resurfacing

An esthetician-owned Houston spa since 2011, now in Greenway Plaza on the River Oaks edge of Upper Kirby. Waxing, facials and massage share the roof with a full medical spa. 4.9★ across 507 Google reviews.

Women-owned, esthetician-founded in 2011Brazilian waxing, for men tooBotox, Dysport, Jeuveau and Restylane fillersNAD+ therapy and GLP-1 weight loss
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2

Houston Premier Dermatology — Medical dermatology first, cosmetics done quietly

·Uptown / Galleria·$$$·HydraFacial

Dr. Catherine Papasakelariou's dermatology practice on Bering Drive near the Galleria, spanning medical skin care and a full injectable and laser menu. 4.9★ across 298 Google reviews.

Medical and cosmetic dermatology under one roofBotox, Dysport, Juvéderm, Sculptra, and KybellaPRP therapy and microneedlingFree parking and coffee bar
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3

Bare Necessities Spa + MedSpa - Tanglewood — Waxing, facials, and injectables since 2011

·Uptown / Galleria·$$$·HydraFacial

A women-owned Tanglewood spa on S. Voss Road that pairs Brazilian waxing and customized facials with a full medical spa menu. 4.9★ across 309 Google reviews.

Women-ownedBrazilian waxing and customized facialsBotox, Dysport, Jeuveau, and Restylane fillersNAD+ therapy and B12 injections
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4

Clearstone Laser Hair Removal & Med Spa — Laser hair removal as the main event

·Uptown / Galleria·$$$·Laser hair removal

A Post Oak Boulevard med spa near the Galleria that has focused on laser hair removal since 2009, with IPL photofacials, microneedling, and injectables alongside. 4.8★ across 389 Google reviews.

Laser hair removal specialists since 200950,000+ treatments across six Houston-area locationsCynosure and Epicare laser systemsIPL photofacials, microneedling, and VI Peels
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5

Whole Health Center Houston — Family functional medicine with a faith streak

·Uptown / Galleria·$$·Allograft Cellular Therapy

Women-owned functional medicine and nutrition practice near the Galleria, led by Dr. Valeska Wells, treating everything a family doctor would with natural-first methods. 4.6★ across 56 Google reviews.

Women-ownedPRP and prolozone injectionsChelation and infusion therapiesBotox and microneedling on site
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Frequently Asked Questions

What is Botox & Injectables?+
Injectable botulinum toxin used to temporarily relax muscles that cause expression wrinkles.
Where can I get Botox & Injectables in Uptown / Galleria?+
Bare Necessities Spa + MedSpa – Upper Kirby, Houston Premier Dermatology, Bare Necessities Spa + MedSpa - Tanglewood are the top-ranked Botox & Injectables providers in Uptown / Galleria. Pricing sits mostly in the $$$ range — confirm directly with each clinic.