Ranking — Houston
The Best Botox & Injectables in Houston, Ranked (2026)
57 Houston venues offer Botox & Injectables and clear our 4.5★, 50-plus-review quality bar. These are the best, ranked by real customer reviews, local search performance, and AI-citation data — never paid placement.
Written by the WWG editorial team · Max Palmer · Updated 2026-07-18
Ranked from real customer reviews, local search performance, and AI-citation data — not paid placement.
Dr T MedSpa — Small-team med spa, zero sales pressure
A boutique medical spa in Friendswood, on the southern edge of greater Houston. Injectables, facials, and GLP-1 weight-loss support from a small, hands-on team. 5★ across 300 Google reviews.
Dream Aesthetics Medspa — Injectables with a soft touch on Studemont
A downtown-area medical spa on Studemont Street, established in 2017. Injectables, lasers, EmSculpt, and facials in a space reviewers call chic but cozy. 5★ across 453 Google reviews.
SkinCeuticals SkinLab by Dr. Roth — Skin-first injectables on Kirby Drive
A SkinCeuticals-branded skin clinic inside the 2800 Kirby complex in River Oaks. The menu runs from Botox and lip filler to HydraFacials, peels and microneedling. 4.9★ across 1,053 Google reviews.
Z Med Clinic and Med Spa — Weight loss, hormones, and lasers together
A medical spa and weight-loss center on Greenbriar in the Museum District area. Semaglutide programs, hormone therapy, injectables, and laser skin treatments under actual medical supervision. 4.9★ across 576 Google reviews.
Bare Necessities Spa + MedSpa – Upper Kirby — Esthetician-owned spa with a medspa attached
An esthetician-owned Houston spa since 2011, now in Greenway Plaza on the River Oaks edge of Upper Kirby. Waxing, facials and massage share the roof with a full medical spa. 4.9★ across 507 Google reviews.
Anita's Skin Care Clinic — Acne expertise with a curriculum
A facial spa in Cinco Ranch, Katy, specializing in acne treatment, acne scar revision, and customized skincare plans. 5★ across 447 Google reviews.
Clinic 45 — Doctor-led weight loss at volume
A physician-owned medical weight loss practice and med spa on the Gulf Freeway in southeast Houston, pairing GLP-1 programs with a full aesthetics menu. 4.8★ across 1,367 Google reviews.
PurA Medical Aesthetics — Precision injectables, zero pressure
A Museum District med spa on Bissonnet Street offering injectables, PDO threads, Emsculpt, and skin treatments from certified medical professionals. 5★ across 891 Google reviews.
Houston Premier Dermatology — Medical dermatology first, cosmetics done quietly
Dr. Catherine Papasakelariou's dermatology practice on Bering Drive near the Galleria, spanning medical skin care and a full injectable and laser menu. 4.9★ across 298 Google reviews.
Vain Aesthetics & Wellness — Nurse-led aesthetics with a wellness spine
A women-owned, nurse practitioner-led clinic on W Main Street in League City combining injectables and facials with GLP-1 weight management, IV therapy, and TRT. 5★ across 322 Google reviews.
ZO Skin Centre Houston — Skin health first, syringe second
The ZO-brand skin centre on Waugh Drive near River Oaks. Medical aestheticians and nurse injectors build personalized plans around Hydrafacials, peels, lasers, and conservative Botox. 5★ across 250 Google reviews.
Bare Necessities Spa + MedSpa - Tanglewood — Waxing, facials, and injectables since 2011
A women-owned Tanglewood spa on S. Voss Road that pairs Brazilian waxing and customized facials with a full medical spa menu. 4.9★ across 309 Google reviews.